Check out our new article in the Journal of Clinical Investigation. Collaborating with the Salvemini lab, we show how cancer-related cognitive impairment may arise due to cisplatin induced increase of sphingosine-1-phosphate. #cancer #SLU
Our new paper in #eNeuro with our collaborators from the Xu lab is available! In it, we identify the differential effects of GPER signaling on hippocampal and cortical neurons and the receptor's importance in early neuronal development #neurodevelopment #neuroscience #SLU
Such a great time giving a seminar at @kalamazoocollege and seeing a Zhang lab alumni #vcu #vcumedchem
Thanks @kalamazoocollege for the great parking! Excited to give a seminar here today.
Check out our new paper and cover in ACS Chemical Neuroscience that describes new GPER agonists. Special thanks to @bentrospection for creating the cover art and @slu_official for funding the project. #gproteincoupledreceptors #estrogen #drugdiscovery #neuroscience #neurodevelopment
Another great paper about our metabolite tagging technology being developed with the Edwards lab. #metabolism #organicchemistry #isotopes #diabetes #massspectrometry
Check out our new paper with the Edwards group. We still have a lot of exciting things to come from this collaboration for the metabolomics field! #neucode #metabolism #billikenresearch @slu_official
Molecular modeling can be so pretty, but it's strain on the eyes is uncanny #gproteincoupledreceptors #insilico #computermodeling #colerful #lovehurts
Check out our new paper looking at tamoxifen's effect on the zika virus. #virology #tamoxifen #sideproject
Good day to skip lab work! #gradstudentlife #outdoorclassroom #topgolf
And another student graduates! Congrats Nick! #saberchampagne #graduation #organicchemistry #gproteincoupledreceptors
And another student graduates! My custom made champagne saber chemistry spatula worked! #champagne #graduation #saberchampagne
Strychnine total synthesis day in advance synthesis class! #soexcited #organicchemistry #totalsynthesis #colorful
Our new collaboration with Drs. Filardo and Salam from University of Iowa looks at targeting PROTACs to both nuclear and membrane-bound estrogen receptors. A lot more interesting work to follow from this successful collaboration. https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.1c00018#
Check out our new review article about the G Protien-Coupled Estrogen Receptor, GPER, and its potential for the treatment of gallstones. https://www.frontiersin.org/articles/10.3389/fendo.2020.578536/full #estrogen #endocrinology #gallstones #SLU #medicine
Our new article in Bioorganic Chemistry shows the potential of photodeoxygenation as an anticancer therapy. https://www.sciencedirect.com/science/article/abs/pii/S0045206820317405 #cancer #cancersucks #drugdiscovery #SaintLouisUniversity
Our exciting GPR183 drug discovery efforts with the Salvemini lab have led to a new, non-opioid, target for pain. https://jpet.aspetjournals.org/content/375/2 #coverart #coverarticle #pain #opioidcrisis #drugdiscovery #ASPET #JPET #SaintLouisUniversity #SLU
The Arnatt Lab in the chemistry department at Saint Louis University utilizes organic chemistry to decipher cellular processes and disease states, focusing on nuclear proteins and DNA modifications as they pertain to cancer and stem cell biology.
